Forced oscillation technique as a predictor of FEV1 improvement in asthma

Highlights • The usefulness of the forced oscillation technique for untreated asthma is unclear. • We assessed whether FOT could predict a 10% improvement in FEV1. • Respiratory resistance at 5 Hz (R5) of the FOT was an improved parameter. • In the multivariate analyses, the R5 independently predict...

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Veröffentlicht in:	Respiratory physiology & neurobiology 2017-02, Vol.236, p.78-83
Hauptverfasser:	Akamatsu, Taisuke, Shirai, Toshihiro, Shimoda, Yukiko, Suzuki, Takahito, Hayashi, Ichiro, Noguchi, Rie, Mochizuki, Eisuke, Sakurai, Shogo, Saigusa, Mika, Yamamoto, Akito, Shishido, Yuichiro, Akita, Takefumi, Morita, Satoru, Asada, Kazuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - therapeutic use Adrenergic Agonists - therapeutic use Adult Aged Aged, 80 and over Airway Resistance - drug effects Airway Resistance - physiology Anti-Asthmatic Agents - therapeutic use Asthma Asthma - drug therapy Asthma - physiopathology Female FEV1 Forced Expiratory Volume - drug effects Forced Expiratory Volume - physiology Forced oscillation technique Humans Lung function Male Medical Education Middle Aged Nitric Oxide - metabolism Oscillometry - methods Outcome Assessment (Health Care) - methods Pulmonary/Respiratory Regression Analysis Respiratory resistance Retrospective Studies ROC Curve Spirometry Spirometry - methods Vital Capacity - drug effects Vital Capacity - physiology
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Beschreibung
Zusammenfassung:	Highlights • The usefulness of the forced oscillation technique for untreated asthma is unclear. • We assessed whether FOT could predict a 10% improvement in FEV1. • Respiratory resistance at 5 Hz (R5) of the FOT was an improved parameter. • In the multivariate analyses, the R5 independently predicted improvement. • R5 assessed before treatment is a good predictor of an FEV1 improvement of 10%.
ISSN:	1569-9048 1878-1519
DOI:	10.1016/j.resp.2016.11.013