Sex-specific association between functional neuropeptide S receptor gene ( NPSR1 ) variants and cortisol and central stress responses
Highlights • Two independent cohorts with n = 277 and n = 65 healthy females and males. • Two different stress paradigms (TSST and Scan STRESS ), with one being used in the MRI scanner. • Exploratory converging evidence from both substudies for the view that genetic variation in the neuropeptide S r...
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| Veröffentlicht in: | Psychoneuroendocrinology 2017-02, Vol.76, p.49-56 |
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| container_title | Psychoneuroendocrinology |
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| creator | Streit, Fabian Akdeniz, Ceren Haddad, Leila Kumsta, Robert Entringer, Sonja Frank, Josef Yim, Ilona S Zänkert, Sandra Witt, Stephanie H Kirsch, Peter Rietschel, Marcella Wüst, Stefan |
| description | Highlights • Two independent cohorts with n = 277 and n = 65 healthy females and males. • Two different stress paradigms (TSST and Scan STRESS ), with one being used in the MRI scanner. • Exploratory converging evidence from both substudies for the view that genetic variation in the neuropeptide S receptor gene modulates both cortisol responses to acute stress as well as neural stress processing in a sex-specific manner. |
| doi_str_mv | 10.1016/j.psyneuen.2016.10.027 |
| format | Article |
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| ispartof | Psychoneuroendocrinology, 2017-02, Vol.76, p.49-56 |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adolescent Adult Endocrinology & Metabolism Female Humans Hydrocortisone - metabolism Male Polymorphism, Single Nucleotide Psychiatry Receptors, G-Protein-Coupled - genetics Saliva - chemistry Sex Factors Stress, Psychological - genetics Stress, Psychological - metabolism Young Adult |
| title | Sex-specific association between functional neuropeptide S receptor gene ( NPSR1 ) variants and cortisol and central stress responses |
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