Adjuvant intraperitoneal chemotherapy for the treatment of gastric cancer at risk for peritoneal carcinomatosis: A systematic review

The peritoneal surface is a frequent site of recurrence following surgery for gastric cancer. A systematic review and random effect analysis was undertaken to analyze current literature regarding the role of adjuvant intraperitoneal chemotherapy in gastric cancer. While pooled analysis supports the...

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Veröffentlicht in:	Journal of surgical oncology 2017-02, Vol.115 (2), p.192-201
Hauptverfasser:	Feingold, Paul L., Kwong, Mei Li M., Davis, Jeremy L., Rudloff, Udo
Format:	Artikel
Sprache:	eng
Schlagworte:	adjuvant regional chemotherapy Antineoplastic Combined Chemotherapy Protocols - therapeutic use Chemotherapy, Adjuvant Chemotherapy, Cancer, Regional Perfusion gastrointestinal malignancies heated intraperitoneal chemotherapy (HIPEC) Humans Injections, Intraperitoneal peritoneal carcinomatosis Peritoneal Neoplasms - drug therapy Peritoneal Neoplasms - secondary Prognosis Stomach Neoplasms - drug therapy Stomach Neoplasms - pathology systematic review
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Zusammenfassung:	The peritoneal surface is a frequent site of recurrence following surgery for gastric cancer. A systematic review and random effect analysis was undertaken to analyze current literature regarding the role of adjuvant intraperitoneal chemotherapy in gastric cancer. While pooled analysis supports the use of adjuvant IP chemotherapy in resectable gastric cancer, maximal benefit occured with intra‐operative delivery, and possibly the use of MMC. J. Surg. Oncol. 2017;115:192–201. © 2016 Wiley Periodicals, Inc.
ISSN:	0022-4790 1096-9098
DOI:	10.1002/jso.24476