Insecticidal Activity of Huperzine A from the New Zealand Clubmoss, Lycopodium varium

A bioactivity-directed investigation of an extract of the New Zealand clubmoss, Lycopodium varium, collected on subantarctic Campbell Island, has led to the isolation of the alkaloid huperzine A (1) as the major antifeedant and insecticidal component. Huperzine A showed insecticidal activity against...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2002-01, Vol.50 (3), p.491-494
Hauptverfasser:	Ainge, Gary D, Lorimer, Stephen D, Gerard, Philippa J, Ruf, Leslie D
Format:	Artikel
Sprache:	eng
Schlagworte:	Agronomy. Soil science and plant productions Alkaloids Animals Biological and medical sciences Chemical control Cholinesterase Inhibitors - isolation & purification Coleoptera Control Diptera Fundamental and applied biological sciences. Psychology General agronomy. Plant production Generalities. Agricultural and farming systems. Agricultural development Generalities. Production, biomass, yield. Quality Insecticides - isolation & purification Lycopodiaceae - chemistry Moths New Zealand Phytopathology. Animal pests. Plant and forest protection Protozoa. Invertebrates Sesquiterpenes - isolation & purification
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Zusammenfassung:	A bioactivity-directed investigation of an extract of the New Zealand clubmoss, Lycopodium varium, collected on subantarctic Campbell Island, has led to the isolation of the alkaloid huperzine A (1) as the major antifeedant and insecticidal component. Huperzine A showed insecticidal activity against the Australian carpet beetle, Anthrenocerus australis (LD50 = 110 ppm), the Australian sheep blowfly, Lucilia cuprina (LD50 = 2380 ppm), and the webbing clothes moth, Tineola bisselliella (LD50 = 630 ppm). Feeding by A. australis was reduced by 97% at 63 ppm. Keywords: Anthrenocerus australis; Lucilia cuprina; Tineola bisselliella; Lycopodium varium; huperzine A; alkaloid; insecticide
ISSN:	0021-8561 1520-5118
DOI:	10.1021/jf0106087