Emergence of plasmid mediated carbapenemase OXA-48 in a Klebsiella pneumoniae strain in Algeria

A carbapenem resistant Klebsiella pneumoniae strain was isolated in October 2011 in the pediatric unit of the Hôpital central de l’armée in Algeria, this strain have been confirmed for the production of OXA-48 carbapenemase. The blaOXA-48 gene was located on a self conjugative plasmid of 70kb. Multi...

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Veröffentlicht in:Journal of global antimicrobial resistance. 2014-12, Vol.2 (4), p.327-329
Hauptverfasser: Aggoune, Nadjet, Tali-Maamar, Hassiba, Assaous, Farida, Benamrouche, Nabila, Naim, Malek, Rahal, Kheira
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Sprache:eng
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Zusammenfassung:A carbapenem resistant Klebsiella pneumoniae strain was isolated in October 2011 in the pediatric unit of the Hôpital central de l’armée in Algeria, this strain have been confirmed for the production of OXA-48 carbapenemase. The blaOXA-48 gene was located on a self conjugative plasmid of 70kb. Multilocus sequence typing indicated the presence of the sequence type ST-307. This is the first isolation of OXA-48-producing K. pneumoniae in Algeria.
ISSN:2213-7165
2213-7173
DOI:10.1016/j.jgar.2014.06.001