Effect of non-invasive NAVA on the patients with acute exacerbation of chronic obstructive pulmonary disease

To observe the effect of non-invasive neurally adjusted ventilatory assist (NIV-NAVA) on patient-ventilator synchrony and effect of gas exchange in patients with acute exacerbation of chronic obstructive pulmonary disease compared with NIV-pressure support ventilation (PSV). This was a prospective study of 40 patients with AECOPD given 30-min trials of NIV with NIV-PSV group ( =20) and NAVA group ( =20) in random order. Arterial blood gas analysis (ABGs), main asynchrony events and asynchrony index were quantified. There were no significant difference between the two groups on effect of gas exchange ( >0.05). Main asynchrony events during NIV-NAVA including autotriggering, ineffective efforts and double triggering were less frequent than NIV-PSV (