Optimize the cycle of neoadjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma treated with intensity-modulated radiotherapy: A propensity score matching analysis

Highlights • Neoadjuvant chemotherapy has been widely used in advanced nasopharyngeal carcinoma. • The optimal cycle of neoadjuvant chemotherapy has not been defined. • Excessive cycles would result in severe toxicities and economic burden. • Our study firstly found that 2 cycles are enough to achie...

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Veröffentlicht in:	Oral oncology 2016-11, Vol.62, p.78-84
Hauptverfasser:	Peng, Hao, M.D, Chen, Lei, M.D, Li, Wen-Fei, Ph.D, Zhang, Yuan, M.D, Liu, Li-Zhi, M.D, Tian, Li, M.D, Lin, Ai-Hua, Ph.D, Sun, Ying, Ph.D, Ma, Jun, M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Chemoradiotherapy Chemotherapy, Adjuvant Cohort Studies Female Hematology, Oncology and Palliative Medicine Humans Intensity-modulated radiotherapy Locoregionally advanced Male Middle Aged Nasopharyngeal carcinoma Nasopharyngeal Neoplasms - drug therapy Nasopharyngeal Neoplasms - radiotherapy Neoadjuvant chemotherapy Otolaryngology Prognosis Radiotherapy, Intensity-Modulated
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Zusammenfassung:	Highlights • Neoadjuvant chemotherapy has been widely used in advanced nasopharyngeal carcinoma. • The optimal cycle of neoadjuvant chemotherapy has not been defined. • Excessive cycles would result in severe toxicities and economic burden. • Our study firstly found that 2 cycles are enough to achieve survival benefit.
ISSN:	1368-8375 1879-0593
DOI:	10.1016/j.oraloncology.2016.10.014