Core–Shell Gold Nanorod@Metal–Organic Framework Nanoprobes for Multimodality Diagnosis of Glioma

One of the most significant challenges in the diagnosis of brain cancer is efficient in vivo imaging using nontoxic nanoprobes. Core–shell gold nanorod@MIL‐88(Fe) nanostars are successfully constructed as triple‐modality imaging (computed tomography/magnetic‐resonance imaging/photoacoustic imaging)...

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Veröffentlicht in:	Advanced materials (Weinheim) 2017-01, Vol.29 (3), p.n/a
Hauptverfasser:	Shang, Wenting, Zeng, Chaoting, Du, Yang, Hui, Hui, Liang, Xiao, Chi, Chongwei, Wang, Kun, Wang, Zhongliang, Tian, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	Au@MIL‐88(Fe) Biocompatibility Brain Brain cancer Computed tomography Diagnosis Glioma gliomas Gold gold nanorods Humans Imaging Iron Magnetic resonance Medical imaging Metal-Organic Frameworks Multimodal Imaging Nanorods Nanotubes Penetration depth Spatial resolution Toxicity triple modality
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Beschreibung
Zusammenfassung:	One of the most significant challenges in the diagnosis of brain cancer is efficient in vivo imaging using nontoxic nanoprobes. Core–shell gold nanorod@MIL‐88(Fe) nanostars are successfully constructed as triple‐modality imaging (computed tomography/magnetic‐resonance imaging/photoacoustic imaging) nanoprobes that show low cytotoxicity, high contrast, high penetration depth, and high spatial resolution for accurate and noninvasive imaging and diagnosis of gliomas.
ISSN:	0935-9648 1521-4095
DOI:	10.1002/adma.201604381