The prevalence of anxiety and depression in patients with or without hyperhidrosis (HH)

Background There are conflicting data about the correlation between hyperhidrosis (HH) and anxiety and depression. Objective We sought to determine the prevalence of anxiety and depression in patients with or without HH. Methods We examined 2017 consecutive dermatology outpatients from Vancouver, British Columbia, Canada, and Shanghai, China, using Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 scales for anxiety and depression assessments. Multivariable logistic regression analysis was performed to evaluate if the impact of HH on anxiety and depression is dependent on demographic factors and diagnoses of the patients' presenting skin conditions. Results The prevalence of anxiety and depression was 21.3% and 27.2% in patients with HH, respectively, and 7.5% and 9.7% in patients without HH, respectively ( P value