The relationship of A Proliferation-Inducing Ligand expression with the clinical pathology and prognosis in colorectal carcinoma

The relationship of A Proliferation-Inducing Ligand expression with the clinical pathology and prognosis in colorectal carcinoma

To investigate the protein expression of A Proliferation-Inducing Ligand (APRIL) in colorectal cancer (CRC) tissue, and its correlation with clinical pathology and prognosis. One hundred and twenty cases of CRC tissue and related clinical data were collected from the Department of Pathology of Affil...

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Veröffentlicht in:Zhong hua yi xue za zhi 2016-11, Vol.96 (40), p.3232-3235
Hauptverfasser: Mei, H J, Wang, H, Zheng, X B, Jin, Q, Wang, Y, Huang, F, Zhang, S
Format: Artikel
Sprache:chi
Schlagworte:
Cell Differentiation
Colorectal Neoplasms
Humans
Immunohistochemistry
Kaplan-Meier Estimate
Lymphatic Metastasis
Multivariate Analysis
Neoplasm Staging
Prognosis
Proportional Hazards Models
Risk Factors
Survival Rate
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Zusammenfassung:To investigate the protein expression of A Proliferation-Inducing Ligand (APRIL) in colorectal cancer (CRC) tissue, and its correlation with clinical pathology and prognosis. One hundred and twenty cases of CRC tissue and related clinical data were collected from the Department of Pathology of Affiliated Hospital of Nantong University. The specimens were made into tissue microarray. The protein expression of APRIL was detected by Envision immunohistochemistry. The relationship of the protein expression of APRIL with clinicopathological parameters and follow-up data were statistically analyzed. APRIL protein expression positive rate of CRC tissue and cancer adjacent normal mucosal tissue were 83.33% (100/120) and 12.5% (15/120), with a statistical significance (
ISSN:0376-2491
DOI:10.3760/cma.j.issn.0376-2491.2016.40.007