Diuretic, laxative and toxicity studies of Cocculus hirsutus aerial parts
The aqueous extract of the Cocculus hirsutus aerial parts (100 and 200 mg/kg, p.o.) showed significant diuretic activity and laxative effect in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg.
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| Veröffentlicht in: | Fitoterapia 2002-02, Vol.73 (1), p.28-31 |
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| container_end_page | 31 |
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| container_title | Fitoterapia |
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| creator | Ganapaty, S. Dash, G.K. Subburaju, T. Suresh, P. |
| description | The aqueous extract of the
Cocculus hirsutus aerial parts (100 and 200 mg/kg, p.o.) showed significant diuretic activity and laxative effect in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg. |
| doi_str_mv | 10.1016/S0367-326X(01)00345-8 |
| format | Article |
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Cocculus hirsutus aerial parts (100 and 200 mg/kg, p.o.) showed significant diuretic activity and laxative effect in rats. The acute toxicity, orally evaluated in mice, was found to be higher than 3000 mg/kg.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Cathartics - administration & dosage</subject><subject>Cathartics - pharmacology</subject><subject>Cathartics - therapeutic use</subject><subject>Cocculus hirsutus</subject><subject>Constipation - drug therapy</subject><subject>Diarrhea - drug therapy</subject><subject>Diuresis - drug effects</subject><subject>Diuretic activity</subject><subject>Diuretics - administration & dosage</subject><subject>Diuretics - pharmacology</subject><subject>Diuretics - therapeutic use</subject><subject>Dose-Response Relationship, Drug</subject><subject>Female</subject><subject>Gastrointestinal Motility - drug effects</subject><subject>General pharmacology</subject><subject>Laxative activity</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Menispermaceae</subject><subject>Mice</subject><subject>Pharmacognosy. 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Drug treatments</subject><subject>Phytotherapy</subject><subject>Plant Extracts - administration & dosage</subject><subject>Plant Extracts - pharmacology</subject><subject>Plant Extracts - therapeutic use</subject><subject>Plant Structures</subject><subject>Rats</subject><subject>Rats, Wistar</subject><issn>0367-326X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1r3EAMhufQkK_2J7T4ktJCnUqe8dg-hbJt00AghyTQ26DVyHSKd72dGYfk39fJLskxJwnxvJJ4lHqPcIqA9us1aNuUurK_PwF-BtCmLts36vB5fKCOUvoLgLU2uK8OEFtrGguH6uJ7mKLkwF-Kge4phzspaO2LPN4HDvmhSHnyQVIx9sViZJ6GKRV_QkxTnhuSGGgoNhRzeqv2ehqSvNvVY3X788fN4ld5eXV-sfh2WbJpTC6546UHwqrHRlvBzlPT6g5q4ooEhapO_NJqNr2toa-tkMCSG_S-Bwajj9XH7d5NHP9NkrJbhcQyDLSWcUoOWwOtMXYG6y3IcUwpSu82MawoPjgE9-jNPXlzj4IcoHvy5to592F3YFquxL-kdtJm4GQHUGIa-khrDumF0zXqCruZO9tyMuu4CxJd4iBrFh-icHZ-DK-88h8jN42B</recordid><startdate>20020201</startdate><enddate>20020201</enddate><creator>Ganapaty, S.</creator><creator>Dash, G.K.</creator><creator>Subburaju, T.</creator><creator>Suresh, P.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>20020201</creationdate><title>Diuretic, laxative and toxicity studies of Cocculus hirsutus aerial parts</title><author>Ganapaty, S. ; Dash, G.K. ; Subburaju, T. ; Suresh, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-c9cbd0a12f1736e19da783905ac2ae1ea29edb63c4f650f56eae0bc71ddf0c043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Cathartics - administration & dosage</topic><topic>Cathartics - pharmacology</topic><topic>Cathartics - therapeutic use</topic><topic>Cocculus hirsutus</topic><topic>Constipation - drug therapy</topic><topic>Diarrhea - drug therapy</topic><topic>Diuresis - drug effects</topic><topic>Diuretic activity</topic><topic>Diuretics - administration & dosage</topic><topic>Diuretics - pharmacology</topic><topic>Diuretics - therapeutic use</topic><topic>Dose-Response Relationship, Drug</topic><topic>Female</topic><topic>Gastrointestinal Motility - drug effects</topic><topic>General pharmacology</topic><topic>Laxative activity</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Menispermaceae</topic><topic>Mice</topic><topic>Pharmacognosy. 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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Biological and medical sciences Cathartics - administration & dosage Cathartics - pharmacology Cathartics - therapeutic use Cocculus hirsutus Constipation - drug therapy Diarrhea - drug therapy Diuresis - drug effects Diuretic activity Diuretics - administration & dosage Diuretics - pharmacology Diuretics - therapeutic use Dose-Response Relationship, Drug Female Gastrointestinal Motility - drug effects General pharmacology Laxative activity Male Medical sciences Menispermaceae Mice Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Structures Rats Rats, Wistar |
| title | Diuretic, laxative and toxicity studies of Cocculus hirsutus aerial parts |
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