DEPENDENCE OF HEART RATE IN TERMS OF THE DAILY MONITORING INDICATORS ON THE ACTIVITY OF PATHOLOGICAL PROCESS IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

The article studies the dependence of indicators of daily monitoring of heart rate on the pathological process activity in patients with systemic lupus erythematosus. As a result of examination of 83 patients (71 women and 12 men aged 17 - 68) with the first, second and third levels of disease activity (first, second and third group respectively) it was found that: 1) the average, maximum and minimum heart rate in patients with systemic lupus erythematosus during the day is significantly higher than the comparable figures in healthy individuals and the dependence of the increase of heart rate on the progress of disease activity was demonstrated by the results of the evaluation of minimum heart rate and in patients with the third degree of disease activity; 2) the vast majority of indicators of heart rate in patients with systemic lupus erythematosus, evaluated separately in active and passive periods of the day, were above the comparable indicators in healthy individuals and higher in the active period compared to the passive, with statistical significance of differences in average and maximum heart rate; 3) the regularity of an increase of average, maximum and minimum heart rate with the increase of activity of systemic lupus erythematosus is characteristic of patients with high activity of the disease (third degree) and is more pronounced in passive (night) period.