Molecular analysis of lungs from pigs immunized with a mutant transferrin binding protein B-based vaccine and challenged with Haemophilus parasuis

Highlights • Inflammatory response genes were seen in Glässer’s disease by microarray and qPCR. • Lower expression of them was seen in pigs vaccinated with an H. parasuis mutant TbpB. • Cell damage genes were seen in Glässer’s disease by microarray and qPCR. • Lower expression of them was seen in pigs vaccinated with an H. parasuis mutant TbpB. • Gene and protein expression was similar in mutant TbpB vaccinated and healthy pigs