Environmental enrichment prevents anxiety-like behavior induced by progesterone withdrawal in two strains of rats

Highlights • Progesterone withdrawal (PW) increases anxiety-like behavior in both strains of rats. • Fluoxetine prevents anxiety-like behavior induced by PW in Wistar Kyoto rats. • A gradual reduction of progesterone reduces anxiety-like behavior in Wistar rats. • Environmental enrichment prevents a...

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Veröffentlicht in:	Neuroscience 2016-11, Vol.336, p.123-132
Hauptverfasser:	Islas-Preciado, D, López-Rubalcava, C, González-Olvera, J, Gallardo-Tenorio, A, Estrada-Camarena, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Anxiety Agents - pharmacology Anxiety - drug therapy Behavior, Animal - drug effects burying behavior test Environment environmental enrichment Female fluoxetine Fluoxetine - pharmacology gradual reduction of progesterone Neurology Progesterone - pharmacology progesterone withdrawal Rats, Inbred WKY Wistar Kyoto
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Zusammenfassung:	Highlights • Progesterone withdrawal (PW) increases anxiety-like behavior in both strains of rats. • Fluoxetine prevents anxiety-like behavior induced by PW in Wistar Kyoto rats. • A gradual reduction of progesterone reduces anxiety-like behavior in Wistar rats. • Environmental enrichment prevents anxiety-like behavior induced by PW.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2016.08.050