Elucidating the anti-Staphylococcus aureus antibody response by immunoproteomics

Staphylococcus aureus is a notorious pathogen both in‐ and outside hospitals as well as a frequent colonizer in healthy individuals. Immunoproteomics techniques have been employed to shed light on the human adaptive immune response to S. aureus in health and disease. Since priming of immune memory,...

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Veröffentlicht in:Proteomics. Clinical applications 2016-10, Vol.10 (9-10), p.1011-1019
Hauptverfasser: Stentzel, Sebastian, Gläser, Regine, Bröker, Barbara M.
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container_issue 9-10
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container_title Proteomics. Clinical applications
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creator Stentzel, Sebastian
Gläser, Regine
Bröker, Barbara M.
description Staphylococcus aureus is a notorious pathogen both in‐ and outside hospitals as well as a frequent colonizer in healthy individuals. Immunoproteomics techniques have been employed to shed light on the human adaptive immune response to S. aureus in health and disease. Since priming of immune memory, a key property of the adaptive immune system, is the basis of successful vaccination, immunoproteomics holds promise for paving the way to an effective S. aureus vaccine.
doi_str_mv 10.1002/prca.201600050
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subjects 1D immunoblots
2D immunoblots
Animals
Antibacterial antibodies
Antibodies, Bacterial - immunology
Antibodies, Bacterial - metabolism
Antigens, Bacterial - immunology
Bacterial Vaccines - immunology
Gram-positive bacteria
Host-Pathogen Interactions - immunology
Humans
Protein array
Proteomics - methods
Staphylococcus aureus
Staphylococcus aureus - immunology
Suspension array
title Elucidating the anti-Staphylococcus aureus antibody response by immunoproteomics
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