Elucidating the anti-Staphylococcus aureus antibody response by immunoproteomics

Staphylococcus aureus is a notorious pathogen both in‐ and outside hospitals as well as a frequent colonizer in healthy individuals. Immunoproteomics techniques have been employed to shed light on the human adaptive immune response to S. aureus in health and disease. Since priming of immune memory,...

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Veröffentlicht in:Proteomics. Clinical applications 2016-10, Vol.10 (9-10), p.1011-1019
Hauptverfasser: Stentzel, Sebastian, Gläser, Regine, Bröker, Barbara M.
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Sprache:eng
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Zusammenfassung:Staphylococcus aureus is a notorious pathogen both in‐ and outside hospitals as well as a frequent colonizer in healthy individuals. Immunoproteomics techniques have been employed to shed light on the human adaptive immune response to S. aureus in health and disease. Since priming of immune memory, a key property of the adaptive immune system, is the basis of successful vaccination, immunoproteomics holds promise for paving the way to an effective S. aureus vaccine.
ISSN:1862-8346
1862-8354
DOI:10.1002/prca.201600050