Predicting tuberculosis without knowing test specificity

Predicting tuberculosis without knowing test specificity

Since the study by Ho and colleagues did not include both of these patient groups, the specificity of the Xpert MTB/RIF test and the positive predictive value within the given population cannot be correctly calculated from this study. [...]we hardly can be in accord with the calculated prevalence ra...

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Veröffentlicht in:The Lancet infectious diseases 2016-11, Vol.16 (11), p.1221-1222
Hauptverfasser: Koksalan, O Kaya, Keske, Siran, Yasin, Yesim, Kilicaslan, Zeki
Format: Artikel
Sprache:eng
Schlagworte:
Disease
Infectious Disease
Infectious diseases
Mycobacterium
Patients
Tuberculosis
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Zusammenfassung:Since the study by Ho and colleagues did not include both of these patient groups, the specificity of the Xpert MTB/RIF test and the positive predictive value within the given population cannot be correctly calculated from this study. [...]we hardly can be in accord with the calculated prevalence rate (169 of 43 435, 0·39%), since all Xpert MTB/RIF positive results were considered as true positives, which could falsely increase the observed prevalence.
ISSN:1473-3099
1474-4457
DOI:10.1016/S1473-3099(16)30396-6