A novel simplified thrombo-inflammatory score portends poor outcome in diabetic patients following myocardial infarction
We investigated prognostic value of novel simplified thrombo-inflammatory score (sTIPS) in patients with ST-elevation myocardial infarction (STEMI) and diabetes mellitus. A total of 465 patients with diabetes mellitus and STEMI were included in the study. Based on admission cut-off values for predic...
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Veröffentlicht in: | Biomarkers in medicine 2016-11, Vol.10 (11), p.1129-1139 |
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Sprache: | eng |
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Zusammenfassung: | We investigated prognostic value of novel simplified thrombo-inflammatory score (sTIPS) in patients with ST-elevation myocardial infarction (STEMI) and diabetes mellitus.
A total of 465 patients with diabetes mellitus and STEMI were included in the study. Based on admission cut-off values for predicting in-hospital mortality of white blood cell count (>13.4 × 10
/mm
) and mean platelet volume-to-platelet count ratio (>0.06), the patients were assigned 0 point for having the lower value of each variable and 1 point for having the upper value of each variable. sTIPS was calculated as the sum of these two variables.
Kaplan-Meier curves demonstrated that higher sTIPS categories were associated with higher in-hospital and 12-month mortality. One-point increment in the score was associated with 51% increase in the risk of in-hospital death and 89% increase in the risk of long term.
sTIPS is useful in predicting worse immediate and long-term outcomes following STEMI. |
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ISSN: | 1752-0363 1752-0371 |
DOI: | 10.2217/bmm-2016-0145 |