Association of swine leukocyte antigen class II haplotypes and immune-related traits in a swine line selected for resistance to mycoplasmal pneumonia

Highlights • We examined association of swine MHC (SLA) class II haplotypes with traits in pigs. • The line studied had improved resistance to mycoplasmal pneumonia of swine (MPS). • Two haplotypes showed increased frequency and decreased MPS lesions. • Two haplotypes, associated with increased MPS...

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Veröffentlicht in:	Comparative immunology, microbiology and infectious diseases microbiology and infectious diseases, 2016-10, Vol.48, p.33-40
Hauptverfasser:	Ando, Asako, Shigenari, Atsuko, Kojima-Shibata, Chihiro, Nakajoh, Mitsuru, Suzuki, Keiichi, Kitagawa, Hitoshi, Shiina, Takashi, Inoko, Hidetoshi, Uenishi, Hirohide
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Breeding Disease association Disease Resistance - genetics Genetic Markers Genotype Haplotype Haplotypes Histocompatibility Antigens Class II - genetics Histocompatibility Antigens Class II - immunology Hydrocortisone - blood Infectious Disease Leukocyte Count Mycoplasmal pneumonia Phagocytosis Phenotype Pneumonia of Swine, Mycoplasmal - genetics Pneumonia of Swine, Mycoplasmal - immunology Pneumonia of Swine, Mycoplasmal - microbiology Pneumonia of Swine, Mycoplasmal - physiopathology Polymorphism, Genetic Swine - immunology Swine leukocyte antigen
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Zusammenfassung:	Highlights • We examined association of swine MHC (SLA) class II haplotypes with traits in pigs. • The line studied had improved resistance to mycoplasmal pneumonia of swine (MPS). • Two haplotypes showed increased frequency and decreased MPS lesions. • Two haplotypes, associated with increased MPS lesions, decreased in frequency. • SLA class II haplotypes are useful markers for breeding to decrease MPS lesions.
ISSN:	0147-9571 1878-1667
DOI:	10.1016/j.cimid.2016.07.004