Pain and Functional Improvement Effects of Methylene Blue Injection on the Soft Tissue Around Fusion Site after Traumatic Thoracolumbar Fixation: A Double-Blind, Randomized Placebo-Controlled Study

Highlights • We assessed effects of MB on pain and ODI after traumatic thoracolumbar fixation. • We analyzed 50 patients who underwent standard posterior pedicular screw fixation. • A single dose of MB (1 ml at a concentration of 0.5%) reduced postoperative pain. • MB was associated with a significa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical neurology and neurosurgery 2016-11, Vol.150, p.6-12
Hauptverfasser:	Farrokhi, Majid Reza, MD, Yazdanpanah, Hamed, MD, Gholami, Mehrnaz, MA, Farrokhi, Farnaz, MD, Mesbahi, Amir Reza, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Body mass index Bone Screws Clinical outcomes Colleges & universities Disability Double-Blind Method Enzyme Inhibitors - administration & dosage Enzyme Inhibitors - adverse effects Enzyme Inhibitors - pharmacology Female Fracture Fixation, Internal - methods Hospital costs Humans Lumbar Vertebrae - surgery Male Methylene blue Methylene Blue - administration & dosage Methylene Blue - adverse effects Methylene Blue - pharmacology Middle Aged Neurology Neurosurgery Outcome Assessment (Health Care) Pain Pain, Postoperative - drug therapy Patients Posterior pedicular screw fixation Postoperative pain Quality of Life Spinal Fractures - surgery Surgery Thoracic Vertebrae - surgery Traumatic thoracolumbar fixation Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • We assessed effects of MB on pain and ODI after traumatic thoracolumbar fixation. • We analyzed 50 patients who underwent standard posterior pedicular screw fixation. • A single dose of MB (1 ml at a concentration of 0.5%) reduced postoperative pain. • MB was associated with a significant improvement in functional QOL. • No side effects or complications related to the use of MB were observed.
ISSN:	0303-8467 1872-6968
DOI:	10.1016/j.clineuro.2016.08.018