Anxiety response and restraint-induced stress differentially affect ethanol intake in female adolescent rats
Highlights • Adolescent female Wistar rats with high anxiety drank more ethanol than average counterparts. • The promoting effect of high anxiety on ethanol intake was inhibited by stress. • Restraint stress increased FOS immunoreactivity in paraventricular nucleus. • Stress-induced FOS immunoreacti...
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Veröffentlicht in: | Neuroscience 2016-10, Vol.334, p.259-274 |
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creator | Acevedo, María Belén Fabio, Maria Carolina Fernández, Macarena Pautassi, Ricardo Marcos |
description | Highlights • Adolescent female Wistar rats with high anxiety drank more ethanol than average counterparts. • The promoting effect of high anxiety on ethanol intake was inhibited by stress. • Restraint stress increased FOS immunoreactivity in paraventricular nucleus. • Stress-induced FOS immunoreactivity was unaffected by level of anxiety response. |
doi_str_mv | 10.1016/j.neuroscience.2016.08.011 |
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Fabio, Maria Carolina ; Fernández, Macarena ; Pautassi, Ricardo Marcos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c520t-47a4dcbc35426b43bea05a0524262ab38ff4b0f2b4f1d32468fba7232437def63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>adolescents</topic><topic>Alcohol Drinking - pathology</topic><topic>Alcohol Drinking - physiopathology</topic><topic>Alcohol Drinking - psychology</topic><topic>Amygdala - metabolism</topic><topic>Amygdala - pathology</topic><topic>Animals</topic><topic>anxiety</topic><topic>Anxiety - pathology</topic><topic>Anxiety - physiopathology</topic><topic>Arcuate Nucleus of Hypothalamus - metabolism</topic><topic>Arcuate Nucleus of Hypothalamus - pathology</topic><topic>Central Nervous System Depressants - administration & dosage</topic><topic>Disease Models, Animal</topic><topic>Ethanol - administration & dosage</topic><topic>ethanol intake</topic><topic>Female</topic><topic>Fos immunoreactivity</topic><topic>Genetic Predisposition to Disease</topic><topic>Multivariate Analysis</topic><topic>Neurology</topic><topic>Paraventricular Hypothalamic Nucleus - metabolism</topic><topic>Paraventricular Hypothalamic Nucleus - pathology</topic><topic>Personality</topic><topic>Proto-Oncogene Proteins c-fos - metabolism</topic><topic>Rats, Wistar</topic><topic>Restraint, Physical</topic><topic>Self Administration</topic><topic>Sexual Maturation</topic><topic>stress</topic><topic>Stress, Psychological - pathology</topic><topic>Stress, Psychological - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Acevedo, María Belén</creatorcontrib><creatorcontrib>Fabio, Maria Carolina</creatorcontrib><creatorcontrib>Fernández, Macarena</creatorcontrib><creatorcontrib>Pautassi, Ricardo Marcos</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><jtitle>Neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Acevedo, María Belén</au><au>Fabio, Maria Carolina</au><au>Fernández, Macarena</au><au>Pautassi, Ricardo Marcos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anxiety response and restraint-induced stress differentially affect ethanol intake in female adolescent rats</atitle><jtitle>Neuroscience</jtitle><addtitle>Neuroscience</addtitle><date>2016-10-15</date><risdate>2016</risdate><volume>334</volume><spage>259</spage><epage>274</epage><pages>259-274</pages><issn>0306-4522</issn><eissn>1873-7544</eissn><abstract>Highlights • Adolescent female Wistar rats with high anxiety drank more ethanol than average counterparts. • The promoting effect of high anxiety on ethanol intake was inhibited by stress. • Restraint stress increased FOS immunoreactivity in paraventricular nucleus. • Stress-induced FOS immunoreactivity was unaffected by level of anxiety response.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>27531856</pmid><doi>10.1016/j.neuroscience.2016.08.011</doi><tpages>16</tpages><oa>free_for_read</oa></addata></record> |
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subjects | adolescents Alcohol Drinking - pathology Alcohol Drinking - physiopathology Alcohol Drinking - psychology Amygdala - metabolism Amygdala - pathology Animals anxiety Anxiety - pathology Anxiety - physiopathology Arcuate Nucleus of Hypothalamus - metabolism Arcuate Nucleus of Hypothalamus - pathology Central Nervous System Depressants - administration & dosage Disease Models, Animal Ethanol - administration & dosage ethanol intake Female Fos immunoreactivity Genetic Predisposition to Disease Multivariate Analysis Neurology Paraventricular Hypothalamic Nucleus - metabolism Paraventricular Hypothalamic Nucleus - pathology Personality Proto-Oncogene Proteins c-fos - metabolism Rats, Wistar Restraint, Physical Self Administration Sexual Maturation stress Stress, Psychological - pathology Stress, Psychological - physiopathology |
title | Anxiety response and restraint-induced stress differentially affect ethanol intake in female adolescent rats |
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