Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value
Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ES...
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| Veröffentlicht in: | Cell stem cell 2016-11, Vol.19 (5), p.569-572 |
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| container_title | Cell stem cell |
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| creator | Yilmaz, Atilgan Peretz, Mordecai Sagi, Ido Benvenisty, Nissim |
| description | Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.
Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling. |
| doi_str_mv | 10.1016/j.stem.2016.10.009 |
| format | Article |
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Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.</description><identifier>ISSN: 1934-5909</identifier><identifier>EISSN: 1875-9777</identifier><identifier>DOI: 10.1016/j.stem.2016.10.009</identifier><identifier>PMID: 27814478</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Genetic Testing ; Genome, Human ; Haploidy ; Human Embryonic Stem Cells - metabolism ; Humans ; Models, Biological ; Reproductive Medicine</subject><ispartof>Cell stem cell, 2016-11, Vol.19 (5), p.569-572</ispartof><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-25e7112c08583fd594938fae8f3616c8b62d604970927038489e5e1cf4012b7a3</citedby><cites>FETCH-LOGICAL-c400t-25e7112c08583fd594938fae8f3616c8b62d604970927038489e5e1cf4012b7a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1934590916303496$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27814478$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yilmaz, Atilgan</creatorcontrib><creatorcontrib>Peretz, Mordecai</creatorcontrib><creatorcontrib>Sagi, Ido</creatorcontrib><creatorcontrib>Benvenisty, Nissim</creatorcontrib><title>Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value</title><title>Cell stem cell</title><addtitle>Cell Stem Cell</addtitle><description>Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.
Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.</description><subject>Genetic Testing</subject><subject>Genome, Human</subject><subject>Haploidy</subject><subject>Human Embryonic Stem Cells - metabolism</subject><subject>Humans</subject><subject>Models, Biological</subject><subject>Reproductive Medicine</subject><issn>1934-5909</issn><issn>1875-9777</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtPwzAQhC0EoqXwBzigHDmQ4FdiG3FBpbRIlTjwuFqOsxGp8ih2gtR_j0OBI6cdjWZHux9C5wQnBJPsepP4HpqEBh2MBGN1gKZEijRWQojDoBXjcaqwmqAT7zcYp4JgcYwmVEjCuZBTtFiZbd1VRbQaGtNGiyZ3u66tbPQcqqM51LW_iVamLqP-HaIltF0DV9F9N-Q1fFtvph7gFB2VpvZw9jNn6PVh8TJfxeun5eP8bh1bjnEf0xQEIdRimUpWFqniisnSgCxZRjIr84wWGeZKYEUFZpJLBSkQW3JMaC4Mm6HLfe_WdR8D-F43lbfhSNNCN3hNJMsE44KTEKX7qHWd9w5KvXVVY9xOE6xHfHqjR3x6xDd6AV9YuvjpH_IGir-VX14hcLsPQPjyswKnva2gtVBUDmyvi676r_8LED1-Aw</recordid><startdate>20161103</startdate><enddate>20161103</enddate><creator>Yilmaz, Atilgan</creator><creator>Peretz, Mordecai</creator><creator>Sagi, Ido</creator><creator>Benvenisty, Nissim</creator><general>Elsevier Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20161103</creationdate><title>Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value</title><author>Yilmaz, Atilgan ; Peretz, Mordecai ; Sagi, Ido ; Benvenisty, Nissim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-25e7112c08583fd594938fae8f3616c8b62d604970927038489e5e1cf4012b7a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Genetic Testing</topic><topic>Genome, Human</topic><topic>Haploidy</topic><topic>Human Embryonic Stem Cells - metabolism</topic><topic>Humans</topic><topic>Models, Biological</topic><topic>Reproductive Medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yilmaz, Atilgan</creatorcontrib><creatorcontrib>Peretz, Mordecai</creatorcontrib><creatorcontrib>Sagi, Ido</creatorcontrib><creatorcontrib>Benvenisty, Nissim</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cell stem cell</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yilmaz, Atilgan</au><au>Peretz, Mordecai</au><au>Sagi, Ido</au><au>Benvenisty, Nissim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value</atitle><jtitle>Cell stem cell</jtitle><addtitle>Cell Stem Cell</addtitle><date>2016-11-03</date><risdate>2016</risdate><volume>19</volume><issue>5</issue><spage>569</spage><epage>572</epage><pages>569-572</pages><issn>1934-5909</issn><eissn>1875-9777</eissn><abstract>Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.
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| source | MEDLINE; Cell Press Free Archives; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Genetic Testing Genome, Human Haploidy Human Embryonic Stem Cells - metabolism Humans Models, Biological Reproductive Medicine |
| title | Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value |
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