Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value

Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ES...

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Veröffentlicht in:Cell stem cell 2016-11, Vol.19 (5), p.569-572
Hauptverfasser: Yilmaz, Atilgan, Peretz, Mordecai, Sagi, Ido, Benvenisty, Nissim
Format: Artikel
Sprache:eng
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Zusammenfassung:Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling. Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.
ISSN:1934-5909
1875-9777
DOI:10.1016/j.stem.2016.10.009