Continuous positive airway pressure treatment impact on memory processes in obstructive sleep apnea patients: a randomized sham-controlled trial

Highlights • The impact of continuous positive airway pressure (CPAP) treatment on a large panel of memory processes in obstructive sleep apnea (OSA) patients is explored. • A randomized, sham-controlled trial using 6 weeks of CPAP versus sham CPAP was conducted. • Three separate memory systems were evaluated: verbal, procedural, and working memory. • Six weeks of CPAP did not improve the memory processes in OSA patients. • The study findings suggest the existence of a complex OSA−neurocognitive relationship.