Muscle MRI in Duchenne muscular dystrophy: Evidence of a distinctive pattern

Highlights • Consistent pattern of muscle involvement on MRI of lower limbs in DMD. • Gluteus medius, minimus and adductor magnus were severely affected at all stages. • Fatty infiltration showed negative correlation with modified MRC grading. • Fatty infiltration showed negative correlation with MD...

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Veröffentlicht in:	Neuromuscular disorders : NMD 2016-11, Vol.26 (11), p.768-774
Hauptverfasser:	Polavarapu, Kiran, Manjunath, Mahadevappa, Preethish-Kumar, Veeramani, Sekar, Deepha, Vengalil, Seena, Thomas, PriyaTreesa, Sathyaprabha, Talakad N, Bharath, Rose Dawn, Nalini, Atchayaram
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - diagnostic imaging Adolescent Child Child, Preschool Cross-Sectional Studies Duchenne muscular dystrophy Humans Image Interpretation, Computer-Assisted Lower Extremity - diagnostic imaging Magnetic Resonance Imaging Muscle imaging Muscle, Skeletal - diagnostic imaging Muscular Dystrophy, Duchenne - diagnostic imaging Neurology Phenotype Prospective Studies Severity of Illness Index
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Beschreibung
Zusammenfassung:	Highlights • Consistent pattern of muscle involvement on MRI of lower limbs in DMD. • Gluteus medius, minimus and adductor magnus were severely affected at all stages. • Fatty infiltration showed negative correlation with modified MRC grading. • Fatty infiltration showed negative correlation with MDFRS scores. • Myoedema and fatty infiltration showed inverse relation in thigh muscles.
ISSN:	0960-8966 1873-2364
DOI:	10.1016/j.nmd.2016.09.002