Effects of Intraoperative Magnesium Sulfate Administration on Postoperative Tramadol Requirement in Liver Transplantation: A Prospective, Double-Blind Study

Abstract Background Magnesium is an N -methyl- d -aspartate receptor blocker and is known to have analgesic effect. Hypomagnesemia can often be seen in liver transplantation and may be associated with higher morbidity and mortality. The objective of this study was to investigate the effects of intra...

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Veröffentlicht in:	Transplantation proceedings 2016-10, Vol.48 (8), p.2742-2746
Hauptverfasser:	Gucyetmez, B, Atalan, H.K, Aslan, S, Yazar, S, Polat, K.Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analgesics, Opioid - administration & dosage Double-Blind Method Female Humans Liver Transplantation - methods Magnesium Sulfate - therapeutic use Male Middle Aged Pain Measurement Pain, Postoperative - drug therapy Prospective Studies Surgery Tramadol - administration & dosage
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Zusammenfassung:	Abstract Background Magnesium is an N -methyl- d -aspartate receptor blocker and is known to have analgesic effect. Hypomagnesemia can often be seen in liver transplantation and may be associated with higher morbidity and mortality. The objective of this study was to investigate the effects of intraoperative magnesium sulfate administration on postoperative tramadol requirement in liver transplant patients. Methods Liver transplant patients >18 years of age were screened prospectively from October 2014 to April 2015. Of these, 35 randomly selected patients with normal blood magnesium level (≥1.8 mmol/L) were included in a control group and another 35 randomly selected patients with low magnesium level (
ISSN:	0041-1345 1873-2623
DOI:	10.1016/j.transproceed.2016.08.033