Influenza Vaccine Research funded by the European Commission FP7-Health-2013-Innovation-1 project

Highlights • Scientific strategies of the EU-funded influenza vaccine consortia are presented. • Global harmonization on immunological assays for influenza is stressed. • A clinical endpoint on reduced influenza symptomology is relevant but challenging. • Novel vaccine concepts can be brought forth...

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Veröffentlicht in:	Vaccine 2016-11, Vol.34 (48), p.5845-5854
Hauptverfasser:	Liu, Heng, PhD, Frijlink, Henderik W., PhD, Huckriede, Anke, PhD, van Doorn, Eva, MSc, Schmidt, Ed, PhD, Leroy, Odile, PhD, Rimmelzwaan, Guus, PhD, McCullough, Keneth, PhD, Whelan, Mike, PhD, Hak, Eelko, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Antigens Biomedical Research - economics Broadly protective Colleges & universities Consortia Correlates of protection Cytotoxicity Enzymes EU consortia European Union Glycoproteins Humans Immune system Immunoglobulins Influenza Influenza Vaccines - administration & dosage Influenza Vaccines - chemistry Influenza, Human - immunology Influenza, Human - prevention & control Mutation Pandemics Pandemics - prevention & control Proteins Research Support as Topic Seasons Vaccines Viruses
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Beschreibung
Zusammenfassung:	Highlights • Scientific strategies of the EU-funded influenza vaccine consortia are presented. • Global harmonization on immunological assays for influenza is stressed. • A clinical endpoint on reduced influenza symptomology is relevant but challenging. • Novel vaccine concepts can be brought forth by formulation studies. • Continuous influenza vaccine efficacy and safety assessments are needed.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2016.10.040