Stem Cell Membrane-Coated Nanogels for Highly Efficient In Vivo Tumor Targeted Drug Delivery

Stem Cell Membrane-Coated Nanogels for Highly Efficient In Vivo Tumor Targeted Drug Delivery

Stem cell membrane‐coated nanogels can effectively evade clearance of the immune system, enhance the tumor targeting properties and antitumor chemotherapy efficacy of gelatin nanogels loaded doxorubicin in mice.

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Bibliographische Detailangaben
Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2016-08, Vol.12 (30), p.4056-4062
Hauptverfasser: Gao, Changyong, Lin, Zhihua, Jurado-Sánchez, Beatriz, Lin, Xiankun, Wu, Zhiguang, He, Qiang
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Anticancer properties
biomimetic nanoparticles
Cell Membrane - chemistry
Doxorubicin
Doxorubicin - administration & dosage
Doxorubicin - therapeutic use
Drug Carriers - chemistry
Drug delivery systems
Drug Delivery Systems - methods
Effectiveness
Female
HeLa Cells
Humans
Immune systems
Mice
Nanoparticles - chemistry
Nanostructure
Nanotechnology
Polyethylene Glycols - chemistry
Polyethyleneimine - chemistry
stem cell membrane
Stem cells
Stem Cells - chemistry
targeted drug delivery
tumor therapy
Tumors
Uterine Cervical Neoplasms - drug therapy
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Beschreibung
Zusammenfassung:Stem cell membrane‐coated nanogels can effectively evade clearance of the immune system, enhance the tumor targeting properties and antitumor chemotherapy efficacy of gelatin nanogels loaded doxorubicin in mice.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.201600624