In vivo terahertz reflection imaging of human scars during and after the healing process

We use terahertz imaging to measure four human skin scars in vivo. Clear contrast between the refractive index of the scar and surrounding tissue was observed for all of the scars, despite some being difficult to see with the naked eye. Additionally, we monitored the healing process of a hypertrophi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of biophotonics 2017-09, Vol.10 (9), p.1143-1151
Hauptverfasser: Fan, Shuting, Ung, Benjamin S. Y., Parrott, Edward P. J., Wallace, Vincent P., Pickwell‐MacPherson, Emma
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We use terahertz imaging to measure four human skin scars in vivo. Clear contrast between the refractive index of the scar and surrounding tissue was observed for all of the scars, despite some being difficult to see with the naked eye. Additionally, we monitored the healing process of a hypertrophic scar. We found that the contrast in the absorption coefficient became less prominent after a few months post‐injury, but that the contrast in the refractive index was still significant even months post‐injury. Our results demonstrate the capability of terahertz imaging to quantitatively measure subtle changes in skin properties and this may be useful for improving scar treatment and management. We investigate hypertrophic scars and normal scars in the terahertz frequencies to demonstrate the capability of terahertz imaging in quantitatively measuring the subtle changes in skin properties. This may be useful for improving scar treatment and management.
ISSN:1864-063X
1864-0648
DOI:10.1002/jbio.201600171