Ovarian cancer presenting as an axillary mass: Case series and literature review
Ovarian cancer is a common cause of death in women worldwide. The purpose of this article was to report a case series and draw physicians’ attention to the benefits of histpathologic techniques in determining uncommon metastatic diseases. In this study, we report a case series of axillary involvemen...
Gespeichert in:
Veröffentlicht in: | Current research in translational medicine 2016-07, Vol.64 (3), p.161-163 |
---|---|
Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Ovarian cancer is a common cause of death in women worldwide. The purpose of this article was to report a case series and draw physicians’ attention to the benefits of histpathologic techniques in determining uncommon metastatic diseases.
In this study, we report a case series of axillary involvement of ovarian cancer in 6 patients. The data were collected between 2006 and 2015 by analyzing patient's characteristics, and biochemical and immunohistochemical features. No pathologic lesions were detected in breasts. Specific immunohistochemical methods such as GCDFP-15, CA12-5, WT-1, and PAX-8 supported evidence of metastasis from ovarian cancer to axillary lymph nodes.
Biochemical tests showed increased levels of CA12-5 in all patients. In 5 patients, GCDFP-15 was negative and WT-1 was positive with specific immunohistochemical staining. PAX-8 was positive in 3 of 5 patients.
Physicians need to be aware that histopathologic and immunohistochemical results can make a significant contribution in determining the true primary tissue of metastatic adenocarcinoma, even in the absence of typical clinical findings. |
---|---|
ISSN: | 2452-3186 2452-3186 |
DOI: | 10.1016/j.retram.2016.04.002 |