High-throughput «Omics» technologies: New tools for the study of triple-negative breast cancer

Highlights • TNBC is a highly diverse group of breast cancer with poor prognosis. • Omics technologies are new tools to improve understanding of TNBC carcinogenesis. • Omics identifies new bio-signatures for TNBC stratification into prognostic profiles. • Statistical analyses of multi-omics data are...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer letters 2016-11, Vol.382 (1), p.77-85
Hauptverfasser:	Judes, Gaëlle, Rifaï, Khaldoun, Daures, Marine, Dubois, Lucas, Bignon, Yves-Jean, Penault-Llorca, Frédérique, Bernard-Gallon, Dominique
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Animals Arrays Bioinformatics Biology Biomarkers Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Breast cancer Cancer therapies Cell cycle Clinical applications Computational Biology Conflicts of interest Databases, Genetic Deoxyribonucleic acid DNA DNA methylation DNA, Neoplasm - genetics DNA, Neoplasm - metabolism Epigenesis, Genetic Epigenetics Epigenomics Epigenomics - methods Female Gene expression Gene Expression Profiling - methods Gene Expression Regulation, Neoplastic Gene Regulatory Networks Genomes Genomics Genomics - methods Growth factors Hematology, Oncology and Palliative Medicine High-Throughput Nucleotide Sequencing Humans Kinases Metabolism Metabolites Molecular Diagnostic Techniques Mutation Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Precision Medicine Predictive Value of Tests Prognosis Protein expression Protein Interaction Maps Proteins Proteomics Proteomics - methods RNA, Neoplasm - genetics RNA, Neoplasm - metabolism Signal transduction Transcriptome Transcriptomics Triple Negative Breast Neoplasms - genetics Triple Negative Breast Neoplasms - metabolism Triple Negative Breast Neoplasms - pathology Triple Negative Breast Neoplasms - therapy Triple-negative breast cancer Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • TNBC is a highly diverse group of breast cancer with poor prognosis. • Omics technologies are new tools to improve understanding of TNBC carcinogenesis. • Omics identifies new bio-signatures for TNBC stratification into prognostic profiles. • Statistical analyses of multi-omics data are necessary to clinical applications.
ISSN:	0304-3835 1872-7980
DOI:	10.1016/j.canlet.2016.03.001