Knockout Corner: Knockout mice for monoamine oxidase A
A line of transgenic mice was isolated in which transgene integration had caused a deletion in the gene encoding monoamine oxidase A, an enzyme that degrades serotonin and norepinephrine. This has provided an animal model of MAOA deficiency in humans, a condition characterized by borderline mental r...
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Veröffentlicht in: | The international journal of neuropsychopharmacology 1999-09, Vol.2 (3), p.241-243, Article S1461145799001534 |
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container_title | The international journal of neuropsychopharmacology |
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creator | Seif, Isabelle De Maeyer, Edward |
description | A line of transgenic mice was isolated in which transgene integration had caused a deletion in the gene
encoding monoamine oxidase A, an enzyme that degrades serotonin and norepinephrine. This has provided
an animal model of MAOA deficiency in humans, a condition characterized by borderline mental retardation
and impulsive aggression. |
doi_str_mv | 10.1017/S1461145799001534 |
format | Article |
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ispartof | The international journal of neuropsychopharmacology, 1999-09, Vol.2 (3), p.241-243, Article S1461145799001534 |
issn | 1461-1457 1469-5111 |
language | eng |
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source | Access via Oxford University Press (Open Access Collection); EZB-FREE-00999 freely available EZB journals |
subjects | Trends and Perspectives |
title | Knockout Corner: Knockout mice for monoamine oxidase A |
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