Knockout Corner: Knockout mice for monoamine oxidase A

Knockout Corner: Knockout mice for monoamine oxidase A

A line of transgenic mice was isolated in which transgene integration had caused a deletion in the gene encoding monoamine oxidase A, an enzyme that degrades serotonin and norepinephrine. This has provided an animal model of MAOA deficiency in humans, a condition characterized by borderline mental r...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The international journal of neuropsychopharmacology 1999-09, Vol.2 (3), p.241-243, Article S1461145799001534
Hauptverfasser: Seif, Isabelle, De Maeyer, Edward
Format: Artikel
Sprache:eng
Schlagworte:
Trends and Perspectives
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A line of transgenic mice was isolated in which transgene integration had caused a deletion in the gene encoding monoamine oxidase A, an enzyme that degrades serotonin and norepinephrine. This has provided an animal model of MAOA deficiency in humans, a condition characterized by borderline mental retardation and impulsive aggression.
ISSN:1461-1457
1469-5111
DOI:10.1017/S1461145799001534