Detection of circulating tumour cells may add value in endometrial cancer management

Abstract Objective To evaluate the role of circulating tumour cells (CTCs) in patients with endometrial cancer (EC). Study design This study included 40 patients with a pre-operative diagnosis of high-risk EC between April 2015 and May 2016. Patients were further divided into high-risk (grade 3, non...

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Veröffentlicht in:	European journal of obstetrics & gynecology and reproductive biology 2016-12, Vol.207, p.1-4
Hauptverfasser:	Ni, T, Sun, X, Shan, B, Wang, J, Liu, Y, Gu, S.-L, Wang, Y.-D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers, Tumor - blood CA-125 Antigen - blood CA125 Carcinoma, Endometrioid - blood Carcinoma, Endometrioid - pathology Carcinoma, Endometrioid - secondary Carcinoma, Endometrioid - therapy Cervix Uteri - drug effects Cervix Uteri - pathology Cervix Uteri - surgery Chemotherapy, Adjuvant Circulating tumour cells Cystadenocarcinoma, Serous - blood Cystadenocarcinoma, Serous - pathology Cystadenocarcinoma, Serous - secondary Cystadenocarcinoma, Serous - therapy Endometrial cancer Endometrial Neoplasms - blood Endometrial Neoplasms - pathology Endometrial Neoplasms - prevention & control Endometrial Neoplasms - therapy Endometrium - drug effects Endometrium - pathology Endometrium - surgery Female Follow-Up Studies HE4 Humans Membrane Proteins - blood Middle Aged Myometrium - drug effects Myometrium - pathology Myometrium - surgery Neoplasm Grading Neoplasm Invasiveness Neoplasm Recurrence, Local - prevention & control Neoplasm Staging Neoplastic Cells, Circulating - drug effects Neoplastic Cells, Circulating - pathology Obstetrics and Gynecology Proteins - analysis Uterine Cervical Neoplasms - drug therapy Uterine Cervical Neoplasms - prevention & control Uterine Cervical Neoplasms - secondary Uterine Cervical Neoplasms - surgery Uterine Neoplasms - drug therapy Uterine Neoplasms - prevention & control Uterine Neoplasms - secondary Uterine Neoplasms - surgery
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Zusammenfassung:	Abstract Objective To evaluate the role of circulating tumour cells (CTCs) in patients with endometrial cancer (EC). Study design This study included 40 patients with a pre-operative diagnosis of high-risk EC between April 2015 and May 2016. Patients were further divided into high-risk (grade 3, non-endometrioid, myometrial invasion ≥1/2 and stage III–IV) and high-intermediate-risk (grade 2–3, endometrioid, myometrial invasion
ISSN:	0301-2115 1872-7654
DOI:	10.1016/j.ejogrb.2016.09.031