Is the inactivation of dentin proteases by crosslinkers reversible?

Highlights • This study evaluated the reversibility of the inactivation of dentin proteases by crosslinkers. • The results confirm the longterm inhibitory effect of crosslinkers on dentin matrix. • The study indicated that the longterm effect is both crosslinker and dose-dependent.

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Veröffentlicht in:Dental materials 2017-02, Vol.33 (2), p.e62-e68
Hauptverfasser: Seseogullari-Dirihan, Roda, Mutluay, Mustafa Murat, Pashley, David H, Tezvergil-Mutluay, Arzu
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container_end_page e68
container_issue 2
container_start_page e62
container_title Dental materials
container_volume 33
creator Seseogullari-Dirihan, Roda
Mutluay, Mustafa Murat
Pashley, David H
Tezvergil-Mutluay, Arzu
description Highlights • This study evaluated the reversibility of the inactivation of dentin proteases by crosslinkers. • The results confirm the longterm inhibitory effect of crosslinkers on dentin matrix. • The study indicated that the longterm effect is both crosslinker and dose-dependent.
doi_str_mv 10.1016/j.dental.2016.09.036
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Advanced Basic Science
Collagen
Crosslinkers
Cysteine cathepsins
Degradation
Dentin
Dentin - enzymology
Dentistry
Glutaral
Matrix Metalloproteinases
Peptide Hydrolases - metabolism
title Is the inactivation of dentin proteases by crosslinkers reversible?
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