Is the inactivation of dentin proteases by crosslinkers reversible?

Is the inactivation of dentin proteases by crosslinkers reversible?

Highlights • This study evaluated the reversibility of the inactivation of dentin proteases by crosslinkers. • The results confirm the longterm inhibitory effect of crosslinkers on dentin matrix. • The study indicated that the longterm effect is both crosslinker and dose-dependent.

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Bibliographische Detailangaben
Veröffentlicht in:Dental materials 2017-02, Vol.33 (2), p.e62-e68
Hauptverfasser: Seseogullari-Dirihan, Roda, Mutluay, Mustafa Murat, Pashley, David H, Tezvergil-Mutluay, Arzu
Format: Artikel
Sprache:eng
Schlagworte:
Advanced Basic Science
Collagen
Crosslinkers
Cysteine cathepsins
Degradation
Dentin
Dentin - enzymology
Dentistry
Glutaral
Matrix Metalloproteinases
Peptide Hydrolases - metabolism
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Zusammenfassung:Highlights • This study evaluated the reversibility of the inactivation of dentin proteases by crosslinkers. • The results confirm the longterm inhibitory effect of crosslinkers on dentin matrix. • The study indicated that the longterm effect is both crosslinker and dose-dependent.
ISSN:0109-5641
1879-0097
DOI:10.1016/j.dental.2016.09.036