Prevention of Peripartum Hepatitis B Transmission
To the Editor: Pan et al. (June 16 issue) 1 found that antiviral therapy has an important role in the elimination of mother-to-child transmission of hepatitis B virus (HBV). Their results add value to the efforts of defining strategies that will bring us closer to the goal of global elimination of H...
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| Veröffentlicht in: | The New England journal of medicine 2016-10, Vol.375 (15), p.1496-1498 |
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| container_end_page | 1498 |
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| container_issue | 15 |
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| container_title | The New England journal of medicine |
| container_volume | 375 |
| creator | Fan, Rong Yin, Xueru Hou, Jinlin Jindal, Ankur Singh, Avishek Sarin, Shiv K Yang, Feng-Shuo Pan, Calvin Q Han, Guorong Wang, Yuming |
| description | To the Editor:
Pan et al. (June 16 issue)
1
found that antiviral therapy has an important role in the elimination of mother-to-child transmission of hepatitis B virus (HBV). Their results add value to the efforts of defining strategies that will bring us closer to the goal of global elimination of HBV infection by 2030.
2
In this trial, treatment with tenofovir disoproxil fumarate (TDF) that was started at 30 to 32 weeks of gestation resulted in 68% of mothers having an HBV DNA level of less than 200,000 IU per milliliter at delivery, which meant that almost one third of mothers . . . |
| doi_str_mv | 10.1056/NEJMc1609991 |
| format | Article |
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Pan et al. (June 16 issue)
1
found that antiviral therapy has an important role in the elimination of mother-to-child transmission of hepatitis B virus (HBV). Their results add value to the efforts of defining strategies that will bring us closer to the goal of global elimination of HBV infection by 2030.
2
In this trial, treatment with tenofovir disoproxil fumarate (TDF) that was started at 30 to 32 weeks of gestation resulted in 68% of mothers having an HBV DNA level of less than 200,000 IU per milliliter at delivery, which meant that almost one third of mothers . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMc1609991</identifier><identifier>PMID: 27732821</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Antiretroviral drugs ; Antiviral agents ; Deoxyribonucleic acid ; DNA ; Gestation ; Hepatitis ; Hepatitis B ; Hepatitis B - prevention & control ; Hepatitis B Surface Antigens ; Hepatitis B Vaccines ; Humans ; Infectious Disease Transmission, Vertical - prevention & control ; Peripartum Period ; Pregnancy Complications, Infectious ; Tenofovir</subject><ispartof>The New England journal of medicine, 2016-10, Vol.375 (15), p.1496-1498</ispartof><rights>Copyright © 2016 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c362t-221f918fdc2c161c749494aa44671825177e992ceb8aaf953a6b001bdb7c5213</citedby><cites>FETCH-LOGICAL-c362t-221f918fdc2c161c749494aa44671825177e992ceb8aaf953a6b001bdb7c5213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMc1609991$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1828841430?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,778,782,2748,2749,26090,27911,27912,52369,54051,64370,64372,64374,72224</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27732821$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fan, Rong</creatorcontrib><creatorcontrib>Yin, Xueru</creatorcontrib><creatorcontrib>Hou, Jinlin</creatorcontrib><creatorcontrib>Jindal, Ankur</creatorcontrib><creatorcontrib>Singh, Avishek</creatorcontrib><creatorcontrib>Sarin, Shiv K</creatorcontrib><creatorcontrib>Yang, Feng-Shuo</creatorcontrib><creatorcontrib>Pan, Calvin Q</creatorcontrib><creatorcontrib>Han, Guorong</creatorcontrib><creatorcontrib>Wang, Yuming</creatorcontrib><title>Prevention of Peripartum Hepatitis B Transmission</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
Pan et al. (June 16 issue)
1
found that antiviral therapy has an important role in the elimination of mother-to-child transmission of hepatitis B virus (HBV). Their results add value to the efforts of defining strategies that will bring us closer to the goal of global elimination of HBV infection by 2030.
2
In this trial, treatment with tenofovir disoproxil fumarate (TDF) that was started at 30 to 32 weeks of gestation resulted in 68% of mothers having an HBV DNA level of less than 200,000 IU per milliliter at delivery, which meant that almost one third of mothers . . .</description><subject>Antiretroviral drugs</subject><subject>Antiviral agents</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>Gestation</subject><subject>Hepatitis</subject><subject>Hepatitis B</subject><subject>Hepatitis B - prevention & control</subject><subject>Hepatitis B Surface Antigens</subject><subject>Hepatitis B Vaccines</subject><subject>Humans</subject><subject>Infectious Disease Transmission, Vertical - prevention & control</subject><subject>Peripartum Period</subject><subject>Pregnancy Complications, Infectious</subject><subject>Tenofovir</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0b1LAzEYBvAgiq3VzVkOdHDwNG--M2qpVqnaofuRS3Nwpfdhcif43xtpFRGHJkOWH08e3hehU8DXgLm4eZk8PVsQWGsNe2gInNKUMSz20RBjolImNR2goxBWOB5g-hANiJSUKAJDBHPv3l3dlU2dNEUyd75sje_6Kpm61nRlV4bkLll4U4eqDCGyY3RQmHVwJ9t3hBb3k8V4ms5eHx7Ht7PUUkG6lBAoNKhiaUlsB1YyHa8xjAkJinCQ0mlNrMuVMYXm1Ig81suXubScAB2hy01s65u33oUui_9bt16b2jV9yEBRzghmQuxKqd6RguKxz640znuEzv_QVdP7Ok4nKqIUA0ZxVFcbZX0TgndF1vqyMv4jA5x9rTL7vcrIz7ahfV655Q_-3l0EFxtQVSGr3ar6P-cTpL-fvA</recordid><startdate>20161013</startdate><enddate>20161013</enddate><creator>Fan, Rong</creator><creator>Yin, Xueru</creator><creator>Hou, Jinlin</creator><creator>Jindal, Ankur</creator><creator>Singh, Avishek</creator><creator>Sarin, Shiv K</creator><creator>Yang, Feng-Shuo</creator><creator>Pan, Calvin Q</creator><creator>Han, Guorong</creator><creator>Wang, Yuming</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20161013</creationdate><title>Prevention of Peripartum Hepatitis B Transmission</title><author>Fan, Rong ; Yin, Xueru ; Hou, Jinlin ; Jindal, Ankur ; Singh, Avishek ; Sarin, Shiv K ; Yang, Feng-Shuo ; Pan, Calvin Q ; Han, Guorong ; Wang, Yuming</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-221f918fdc2c161c749494aa44671825177e992ceb8aaf953a6b001bdb7c5213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Antiretroviral drugs</topic><topic>Antiviral agents</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>Gestation</topic><topic>Hepatitis</topic><topic>Hepatitis B</topic><topic>Hepatitis B - prevention & control</topic><topic>Hepatitis B Surface Antigens</topic><topic>Hepatitis B Vaccines</topic><topic>Humans</topic><topic>Infectious Disease Transmission, Vertical - prevention & control</topic><topic>Peripartum Period</topic><topic>Pregnancy Complications, Infectious</topic><topic>Tenofovir</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fan, Rong</creatorcontrib><creatorcontrib>Yin, Xueru</creatorcontrib><creatorcontrib>Hou, Jinlin</creatorcontrib><creatorcontrib>Jindal, Ankur</creatorcontrib><creatorcontrib>Singh, Avishek</creatorcontrib><creatorcontrib>Sarin, Shiv K</creatorcontrib><creatorcontrib>Yang, Feng-Shuo</creatorcontrib><creatorcontrib>Pan, Calvin Q</creatorcontrib><creatorcontrib>Han, Guorong</creatorcontrib><creatorcontrib>Wang, Yuming</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fan, Rong</au><au>Yin, Xueru</au><au>Hou, Jinlin</au><au>Jindal, Ankur</au><au>Singh, Avishek</au><au>Sarin, Shiv K</au><au>Yang, Feng-Shuo</au><au>Pan, Calvin Q</au><au>Han, Guorong</au><au>Wang, Yuming</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevention of Peripartum Hepatitis B Transmission</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2016-10-13</date><risdate>2016</risdate><volume>375</volume><issue>15</issue><spage>1496</spage><epage>1498</epage><pages>1496-1498</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
Pan et al. (June 16 issue)
1
found that antiviral therapy has an important role in the elimination of mother-to-child transmission of hepatitis B virus (HBV). Their results add value to the efforts of defining strategies that will bring us closer to the goal of global elimination of HBV infection by 2030.
2
In this trial, treatment with tenofovir disoproxil fumarate (TDF) that was started at 30 to 32 weeks of gestation resulted in 68% of mothers having an HBV DNA level of less than 200,000 IU per milliliter at delivery, which meant that almost one third of mothers . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>27732821</pmid><doi>10.1056/NEJMc1609991</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2016-10, Vol.375 (15), p.1496-1498 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Antiretroviral drugs Antiviral agents Deoxyribonucleic acid DNA Gestation Hepatitis Hepatitis B Hepatitis B - prevention & control Hepatitis B Surface Antigens Hepatitis B Vaccines Humans Infectious Disease Transmission, Vertical - prevention & control Peripartum Period Pregnancy Complications, Infectious Tenofovir |
| title | Prevention of Peripartum Hepatitis B Transmission |
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