Meta‐analysis of the association between vitiligo and the level of superoxide dismutase or malondialdehyde
Summary Background There are conflicting reports on the correlation between vitiligo and the levels of either superoxide dismutase (SOD) or malondialdehyde (MDA). Aim To clarify the association between vitiligo and SOD or MDA. Methods Relevant published articles were searched according to our eligib...
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| Veröffentlicht in: | Clinical and experimental dermatology 2017-01, Vol.42 (1), p.21-29 |
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| container_title | Clinical and experimental dermatology |
| container_volume | 42 |
| creator | Shi, M.‐H. Wu, Y. Li, L. Cai, Y.‐F. Liu, M. Gao, X.‐H. Chen, H.‐D. |
| description | Summary
Background
There are conflicting reports on the correlation between vitiligo and the levels of either superoxide dismutase (SOD) or malondialdehyde (MDA).
Aim
To clarify the association between vitiligo and SOD or MDA.
Methods
Relevant published articles were searched according to our eligibility criteria. A meta‐analysis was conducted to pool estimates of the standardized mean difference (SMD) with 95% CI.
Results
Patients with either the active or stable vitiligo had higher levels of both SOD (stable: SMD = 1.61, 95% CI 0.66–2.56, P = 0.001; active: SMD = 2.56, 95% CI 1.13–3.99, P |
| doi_str_mv | 10.1111/ced.12950 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1835415258</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4287661261</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3880-3e4ec846b684c15b66c26c0dc26f591821b1e0124fc15e349ab9d7606ee34ae23</originalsourceid><addsrcrecordid>eNp10btOwzAUBmALgWi5DLwAssQCQ6gvsZOMqFylIhaYI8c-ASMnLnECdOMReEaeBJfSBQkPtmx_5x_OQeiAklMa10SDOaWsEGQDjSmXImGMk000JpxkiSx4PkI7ITwTQjnNxDYasSzjgshsjNwt9Orr41O1yi2CDdjXuH8CrELw2qre-hZX0L8BtPjV9tbZR49Va36Qg1dwy4owzKHz79YANjY0Q68CYN_hRjnfGqucgaeFgT20VSsXYP_33EUPlxf30-tkdnd1Mz2bJZrnOUk4pKDzVFYyTzUVlZSaSU1M3GtR0JzRigKhLK3jL_C0UFVhMkkkxIsCxnfR8Sp33vmXAUJfNjZocE614IdQ0pyLlAom8kiP_tBnP3SxGUslOKOUsaU6WSnd-RA6qMt5ZxvVLUpKyuUIyjiC8mcE0R7-Jg5VE1_Xct3zCCYr8GYdLP5PKqcX56vIb437kRw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1853211228</pqid></control><display><type>article</type><title>Meta‐analysis of the association between vitiligo and the level of superoxide dismutase or malondialdehyde</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Shi, M.‐H. ; Wu, Y. ; Li, L. ; Cai, Y.‐F. ; Liu, M. ; Gao, X.‐H. ; Chen, H.‐D.</creator><creatorcontrib>Shi, M.‐H. ; Wu, Y. ; Li, L. ; Cai, Y.‐F. ; Liu, M. ; Gao, X.‐H. ; Chen, H.‐D.</creatorcontrib><description>Summary
Background
There are conflicting reports on the correlation between vitiligo and the levels of either superoxide dismutase (SOD) or malondialdehyde (MDA).
Aim
To clarify the association between vitiligo and SOD or MDA.
Methods
Relevant published articles were searched according to our eligibility criteria. A meta‐analysis was conducted to pool estimates of the standardized mean difference (SMD) with 95% CI.
Results
Patients with either the active or stable vitiligo had higher levels of both SOD (stable: SMD = 1.61, 95% CI 0.66–2.56, P = 0.001; active: SMD = 2.56, 95% CI 1.13–3.99, P < 0.001) and MDA (stable: SMD = 2.70, 95% CI 1.81–3.59, P < 0.001; active: SMD = 3.50, 95% CI 2.29–4.71, P < 0.001), compared with healthy controls.
Conclusions
This meta‐analysis showed a significant association between vitiligo and high levels of both SOD and MDA.</description><identifier>ISSN: 0307-6938</identifier><identifier>EISSN: 1365-2230</identifier><identifier>DOI: 10.1111/ced.12950</identifier><identifier>PMID: 27735067</identifier><identifier>CODEN: CEDEDE</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Humans ; Malondialdehyde - metabolism ; Oxidative Stress ; Superoxide Dismutase - metabolism ; Vitiligo - metabolism</subject><ispartof>Clinical and experimental dermatology, 2017-01, Vol.42 (1), p.21-29</ispartof><rights>2016 British Association of Dermatologists</rights><rights>2016 British Association of Dermatologists.</rights><rights>Copyright © 2017 British Association of Dermatologists</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3880-3e4ec846b684c15b66c26c0dc26f591821b1e0124fc15e349ab9d7606ee34ae23</citedby><cites>FETCH-LOGICAL-c3880-3e4ec846b684c15b66c26c0dc26f591821b1e0124fc15e349ab9d7606ee34ae23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27735067$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shi, M.‐H.</creatorcontrib><creatorcontrib>Wu, Y.</creatorcontrib><creatorcontrib>Li, L.</creatorcontrib><creatorcontrib>Cai, Y.‐F.</creatorcontrib><creatorcontrib>Liu, M.</creatorcontrib><creatorcontrib>Gao, X.‐H.</creatorcontrib><creatorcontrib>Chen, H.‐D.</creatorcontrib><title>Meta‐analysis of the association between vitiligo and the level of superoxide dismutase or malondialdehyde</title><title>Clinical and experimental dermatology</title><addtitle>Clin Exp Dermatol</addtitle><description>Summary
Background
There are conflicting reports on the correlation between vitiligo and the levels of either superoxide dismutase (SOD) or malondialdehyde (MDA).
Aim
To clarify the association between vitiligo and SOD or MDA.
Methods
Relevant published articles were searched according to our eligibility criteria. A meta‐analysis was conducted to pool estimates of the standardized mean difference (SMD) with 95% CI.
Results
Patients with either the active or stable vitiligo had higher levels of both SOD (stable: SMD = 1.61, 95% CI 0.66–2.56, P = 0.001; active: SMD = 2.56, 95% CI 1.13–3.99, P < 0.001) and MDA (stable: SMD = 2.70, 95% CI 1.81–3.59, P < 0.001; active: SMD = 3.50, 95% CI 2.29–4.71, P < 0.001), compared with healthy controls.
Conclusions
This meta‐analysis showed a significant association between vitiligo and high levels of both SOD and MDA.</description><subject>Humans</subject><subject>Malondialdehyde - metabolism</subject><subject>Oxidative Stress</subject><subject>Superoxide Dismutase - metabolism</subject><subject>Vitiligo - metabolism</subject><issn>0307-6938</issn><issn>1365-2230</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10btOwzAUBmALgWi5DLwAssQCQ6gvsZOMqFylIhaYI8c-ASMnLnECdOMReEaeBJfSBQkPtmx_5x_OQeiAklMa10SDOaWsEGQDjSmXImGMk000JpxkiSx4PkI7ITwTQjnNxDYasSzjgshsjNwt9Orr41O1yi2CDdjXuH8CrELw2qre-hZX0L8BtPjV9tbZR49Va36Qg1dwy4owzKHz79YANjY0Q68CYN_hRjnfGqucgaeFgT20VSsXYP_33EUPlxf30-tkdnd1Mz2bJZrnOUk4pKDzVFYyTzUVlZSaSU1M3GtR0JzRigKhLK3jL_C0UFVhMkkkxIsCxnfR8Sp33vmXAUJfNjZocE614IdQ0pyLlAom8kiP_tBnP3SxGUslOKOUsaU6WSnd-RA6qMt5ZxvVLUpKyuUIyjiC8mcE0R7-Jg5VE1_Xct3zCCYr8GYdLP5PKqcX56vIb437kRw</recordid><startdate>201701</startdate><enddate>201701</enddate><creator>Shi, M.‐H.</creator><creator>Wu, Y.</creator><creator>Li, L.</creator><creator>Cai, Y.‐F.</creator><creator>Liu, M.</creator><creator>Gao, X.‐H.</creator><creator>Chen, H.‐D.</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201701</creationdate><title>Meta‐analysis of the association between vitiligo and the level of superoxide dismutase or malondialdehyde</title><author>Shi, M.‐H. ; Wu, Y. ; Li, L. ; Cai, Y.‐F. ; Liu, M. ; Gao, X.‐H. ; Chen, H.‐D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3880-3e4ec846b684c15b66c26c0dc26f591821b1e0124fc15e349ab9d7606ee34ae23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Humans</topic><topic>Malondialdehyde - metabolism</topic><topic>Oxidative Stress</topic><topic>Superoxide Dismutase - metabolism</topic><topic>Vitiligo - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shi, M.‐H.</creatorcontrib><creatorcontrib>Wu, Y.</creatorcontrib><creatorcontrib>Li, L.</creatorcontrib><creatorcontrib>Cai, Y.‐F.</creatorcontrib><creatorcontrib>Liu, M.</creatorcontrib><creatorcontrib>Gao, X.‐H.</creatorcontrib><creatorcontrib>Chen, H.‐D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical and experimental dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shi, M.‐H.</au><au>Wu, Y.</au><au>Li, L.</au><au>Cai, Y.‐F.</au><au>Liu, M.</au><au>Gao, X.‐H.</au><au>Chen, H.‐D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Meta‐analysis of the association between vitiligo and the level of superoxide dismutase or malondialdehyde</atitle><jtitle>Clinical and experimental dermatology</jtitle><addtitle>Clin Exp Dermatol</addtitle><date>2017-01</date><risdate>2017</risdate><volume>42</volume><issue>1</issue><spage>21</spage><epage>29</epage><pages>21-29</pages><issn>0307-6938</issn><eissn>1365-2230</eissn><coden>CEDEDE</coden><abstract>Summary
Background
There are conflicting reports on the correlation between vitiligo and the levels of either superoxide dismutase (SOD) or malondialdehyde (MDA).
Aim
To clarify the association between vitiligo and SOD or MDA.
Methods
Relevant published articles were searched according to our eligibility criteria. A meta‐analysis was conducted to pool estimates of the standardized mean difference (SMD) with 95% CI.
Results
Patients with either the active or stable vitiligo had higher levels of both SOD (stable: SMD = 1.61, 95% CI 0.66–2.56, P = 0.001; active: SMD = 2.56, 95% CI 1.13–3.99, P < 0.001) and MDA (stable: SMD = 2.70, 95% CI 1.81–3.59, P < 0.001; active: SMD = 3.50, 95% CI 2.29–4.71, P < 0.001), compared with healthy controls.
Conclusions
This meta‐analysis showed a significant association between vitiligo and high levels of both SOD and MDA.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>27735067</pmid><doi>10.1111/ced.12950</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0307-6938 |
| ispartof | Clinical and experimental dermatology, 2017-01, Vol.42 (1), p.21-29 |
| issn | 0307-6938 1365-2230 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1835415258 |
| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Alma/SFX Local Collection |
| subjects | Humans Malondialdehyde - metabolism Oxidative Stress Superoxide Dismutase - metabolism Vitiligo - metabolism |
| title | Meta‐analysis of the association between vitiligo and the level of superoxide dismutase or malondialdehyde |
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