Meta‐analysis of the association between vitiligo and the level of superoxide dismutase or malondialdehyde

Summary Background There are conflicting reports on the correlation between vitiligo and the levels of either superoxide dismutase (SOD) or malondialdehyde (MDA). Aim To clarify the association between vitiligo and SOD or MDA. Methods Relevant published articles were searched according to our eligib...

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Veröffentlicht in:Clinical and experimental dermatology 2017-01, Vol.42 (1), p.21-29
Hauptverfasser: Shi, M.‐H., Wu, Y., Li, L., Cai, Y.‐F., Liu, M., Gao, X.‐H., Chen, H.‐D.
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Sprache:eng
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Zusammenfassung:Summary Background There are conflicting reports on the correlation between vitiligo and the levels of either superoxide dismutase (SOD) or malondialdehyde (MDA). Aim To clarify the association between vitiligo and SOD or MDA. Methods Relevant published articles were searched according to our eligibility criteria. A meta‐analysis was conducted to pool estimates of the standardized mean difference (SMD) with 95% CI. Results Patients with either the active or stable vitiligo had higher levels of both SOD (stable: SMD = 1.61, 95% CI 0.66–2.56, P = 0.001; active: SMD = 2.56, 95% CI 1.13–3.99, P 
ISSN:0307-6938
1365-2230
DOI:10.1111/ced.12950