Secondary hyperparathyroidism prevalence and prognostic role in elderly males with heart failure

Aim Evaluation of secondary hyperparathyroidism (SHPT) and its prognostic impact on all-cause mortality in elderly males with heart failure (HF). Methods Seventy three males (67 ± 7 years old) with systolic HF were included. Baseline PTH was measured. Patients were grouped according to PTH cut-off l...

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Veröffentlicht in:Journal of endocrinological investigation 2017-03, Vol.40 (3), p.297-304
Hauptverfasser: Loncar, G., Bozic, B., Cvetinovic, N., Dungen, H.-D., Lainscak, M., von Haehling, S., Doehner, W., Radojicic, Z., Putnikovic, B., Trippel, T., Popovic, V.
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Sprache:eng
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Zusammenfassung:Aim Evaluation of secondary hyperparathyroidism (SHPT) and its prognostic impact on all-cause mortality in elderly males with heart failure (HF). Methods Seventy three males (67 ± 7 years old) with systolic HF were included. Baseline PTH was measured. Patients were grouped according to PTH cut-off levels of 65 pg/ml (>65 pg/ml = SHPT vs. normal PTH). All-cause mortality was evaluated at 6-year follow-up. Results SHPT was diagnosed in 43 (59 %) patients. They were more severe compared to the patients with normal PTH regarding NYHA functional class (2.4 ± 0.5 vs. 2.1 ± 0.2, p  = 0.001), quality of life score (34 ± 14 vs. 24 ± 12, p  = 0.005), 6-min walking distance (378 ± 79 vs. 446 ± 73 m, p  
ISSN:1720-8386
0391-4097
1720-8386
DOI:10.1007/s40618-016-0561-2