An open-label randomized controlled clinical trial for comparison of continuous phenylephrine versus norepinephrine infusion in prevention of spinal hypotension during cesarean delivery

Highlights • Hypotension is common during spinal anesthesia for cesarean delivery. • Fixed-rate infusions of norepinephrine vs phenylephrine were compared. • Both regimens were effective with similar requirement for rescue boluses. • Norepinephrine can be considered as an alternative to phenylephrin...

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Veröffentlicht in:	International journal of obstetric anesthesia 2017-02, Vol.29, p.18-25
Hauptverfasser:	Vallejo, M.C, Attaallah, A.F, Elzamzamy, O.M, Cifarelli, D.T, Phelps, A.L, Hobbs, G.R, Shapiro, R.E, Ranganathan, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthesia & Perioperative Care Anesthesia, Obstetrical - adverse effects Anesthesia, Spinal - adverse effects Cesarean delivery Cesarean Section - adverse effects Female Humans Hypotension - prevention & control Infusions, Intravenous Norepinephrine Norepinephrine - therapeutic use Obstetrics and Gynecology Phenylephrine Phenylephrine - therapeutic use Pregnancy Spinal anesthesia Treatment Outcome Vasoconstrictor Agents - therapeutic use
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Zusammenfassung:	Highlights • Hypotension is common during spinal anesthesia for cesarean delivery. • Fixed-rate infusions of norepinephrine vs phenylephrine were compared. • Both regimens were effective with similar requirement for rescue boluses. • Norepinephrine can be considered as an alternative to phenylephrine.
ISSN:	0959-289X 1532-3374
DOI:	10.1016/j.ijoa.2016.08.005