Brain Metastasis Prediction by Transcriptomic Profiling in Triple-Negative Breast Cancer

Micro-Abstract We investigated expression of 29,369 gene transcripts in primary tumor samples from 119 patients with advanced triple-negative breast cancer to identify genes with different expression between patients with and without brain metastases (BM). Our results indicate that analysis based on...

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Veröffentlicht in:	Clinical breast cancer 2017-04, Vol.17 (2), p.e65-e75
Hauptverfasser:	Duchnowska, Renata, Jarząb, Michał, Żebracka-Gala, Jadwiga, Matkowski, Rafał, Kowalczyk, Anna, Radecka, Barbara, Kowalska, Małgorzata, Pfeifer, Aleksandra, Foszczyńska-Kłoda, Małgorzata, Musolino, Antonino, Czartoryska-Arłukowicz, Bogumiła, Litwiniuk, Maria, Surus-Hyla, Anna, Szabłowska-Siwik, Sylwia, Karczmarek-Borowska, Bożenna, Dębska-Szmich, Sylwia, Głodek-Sutek, Beata, Sosińska-Mielcarek, Katarzyna, Chmielowska, Ewa, Kalinka-Warzocha, Ewa, Olszewski, Wojciech P, Patera, Janusz, Żawrocki, Anton, Pliszka, Agnieszka, Tyszkiewicz, Tomasz, Rusinek, Dagmara, Oczko-Wojciechowska, Małgorzata, Jassem, Jacek, Biernat, Wojciech
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - metabolism Brain metastasis Brain Neoplasms - diagnosis Brain Neoplasms - epidemiology Brain Neoplasms - secondary cDNA-mediated annealing, extension, and ligation (DASL) assay Estrogen Receptor alpha - metabolism Female Follow-Up Studies Gene Expression Profiling Gene Expression Regulation, Neoplastic Hematology, Oncology and Palliative Medicine Humans Middle Aged Neoplasm Staging Obstetrics and Gynecology Prognosis Receptor, ErbB-2 - metabolism Receptors, Progesterone - metabolism Retrospective Studies Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Selection Transcriptomic profiling Triple negative breast cancer Triple Negative Breast Neoplasms - genetics Triple Negative Breast Neoplasms - pathology
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