Drug Repurposing: New Treatments for Zika Virus Infection?

To date, no antiviral agents have been approved for treating Zika virus (ZIKV) infection. Two recent drug-repurposing studies published in Cell Host & Microbe and Nature Medicine demonstrated that screening FDA-approved drugs for antiviral activity is a promising strategy for identifying therape...

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Veröffentlicht in:	Trends in molecular medicine 2016-11, Vol.22 (11), p.919-921
Hauptverfasser:	Cheng, Feixiong, Murray, James L, Rubin, Donald H
Format:	Artikel
Sprache:	eng
Schlagworte:	antiviral Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Drug Repositioning - methods drug repurposing Humans mechanism-of-action Pathology Signal Transduction - drug effects Zika virus Zika Virus - drug effects Zika Virus Infection - drug therapy Zika Virus Infection - metabolism
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Beschreibung
Zusammenfassung:	To date, no antiviral agents have been approved for treating Zika virus (ZIKV) infection. Two recent drug-repurposing studies published in Cell Host & Microbe and Nature Medicine demonstrated that screening FDA-approved drugs for antiviral activity is a promising strategy for identifying therapeutics with novel activity against ZIKV infection.
ISSN:	1471-4914 1471-499X
DOI:	10.1016/j.molmed.2016.09.006