The efficacy and safety of teriflunomide based therapy in patients with relapsing multiple sclerosis: A meta-analysis of randomized controlled trials

Highlights • Current randomized controlled trials were included in this meta-analysis. • Teriflunomide significantly reduces annualized relapse rates of multiple sclerosis. • Teriflunomide also reduces disability progression of multiple sclerosis. • Teriflunomide has a similar safety and tolerabilit...

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Veröffentlicht in:	Journal of clinical neuroscience 2016-11, Vol.33, p.28-31
Hauptverfasser:	Xu, Min, Lu, Xuesheng, Fang, Jing, Zhu, Xiaoqi, Wang, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	Crotonates - adverse effects Crotonates - pharmacology Humans Meta-analysis Multiple sclerosis Multiple Sclerosis, Relapsing-Remitting - drug therapy Neurology Outcome Assessment (Health Care) Randomized controlled trial Randomized Controlled Trials as Topic Teriflunomide Toluidines - adverse effects Toluidines - pharmacology
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Zusammenfassung:	Highlights • Current randomized controlled trials were included in this meta-analysis. • Teriflunomide significantly reduces annualized relapse rates of multiple sclerosis. • Teriflunomide also reduces disability progression of multiple sclerosis. • Teriflunomide has a similar safety and tolerability profile to placebo.
ISSN:	0967-5868 1532-2653
DOI:	10.1016/j.jocn.2016.02.041