New weapons in the Cryptococcus infection toolkit

Highlights • Cryptococcus neoformans is a leading cause of mortality in immunocompromised patients. • The Cryptococcus :phagocyte interaction profoundly impacts the outcome of infection. • Several new cryptococcal virulence factors have recently been characterised. • These include morphological dive...

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Veröffentlicht in:	Current opinion in microbiology 2016-12, Vol.34, p.67-74
Hauptverfasser:	Taylor-Smith, Leanne M, May, Robin C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Central Nervous System - microbiology Cryptococcosis - microbiology Cryptococcus neoformans - cytology Cryptococcus neoformans - growth & development Cryptococcus neoformans - metabolism Cryptococcus neoformans - pathogenicity Disease Models, Animal Host-Pathogen Interactions Humans Pathology Phagocytes - microbiology Virulence Virulence Factors
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Zusammenfassung:	Highlights • Cryptococcus neoformans is a leading cause of mortality in immunocompromised patients. • The Cryptococcus :phagocyte interaction profoundly impacts the outcome of infection. • Several new cryptococcal virulence factors have recently been characterised. • These include morphological diversity and novel fungal communication strategies.
ISSN:	1369-5274 1879-0364
DOI:	10.1016/j.mib.2016.07.018