Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope

Among 560 patients hospitalized for syncope, 97 (17.3%) received a diagnosis of pulmonary embolism. In 61 patients, the most proximal location of the embolus was a main pulmonary artery or a lobar artery or the perfusion defect was larger than 25% of the total area of both lungs. Syncope is defined...

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Veröffentlicht in:The New England journal of medicine 2016-10, Vol.375 (16), p.1524-1531
Hauptverfasser: Prandoni, Paolo, Lensing, Anthonie W.A, Prins, Martin H, Ciammaichella, Maurizio, Perlati, Marica, Mumoli, Nicola, Bucherini, Eugenio, Visonà, Adriana, Bova, Carlo, Imberti, Davide, Campostrini, Stefano, Barbar, Sofia
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Sprache:eng
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Zusammenfassung:Among 560 patients hospitalized for syncope, 97 (17.3%) received a diagnosis of pulmonary embolism. In 61 patients, the most proximal location of the embolus was a main pulmonary artery or a lobar artery or the perfusion defect was larger than 25% of the total area of both lungs. Syncope is defined as a transient loss of consciousness that has a rapid onset, short duration, and spontaneous resolution and is believed to be caused by temporary cerebral hypoperfusion. 1 – 3 According to current classifications, syncope can be neurally mediated (i.e., vasovagal, situational, or carotid-sinus syncope), can be caused by orthostatic hypotension (i.e., drug-induced hypotension or hypotension due to primary or secondary autonomic failure or due to volume depletion), or can have a cardiovascular origin (i.e., arrhythmias, structural cardiovascular diseases, or pulmonary embolism). 1 Although pulmonary embolism is included in the differential diagnosis of syncope in most textbooks, rigorously designed studies to . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa1602172