Does age, sex, or ACE genotype affect glucose and insulin responses to strength training?

1 Department of Kinesiology, College of Health and Human Performance, University of Maryland, College Park, Maryland 20742; 2 Division of Cardiology, The Milton S. Hershey Medical Center, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033; 3 Division of Gerontology, University of Maryland School of Medicine, Baltimore, Maryland 21201; 4 Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261; 5 Department of Physical Therapy, University of Maryland Eastern Shore, Princess Anne, Maryland 21853; 6 Nutrition, Exercise, and Sarcopenia Laboratory, The Jean Mayer United States Department of Agriculture, Human Nutrition Research Center On Aging at Tufts University, Boston, Massachusetts 02111; and 7 National Institute on Aging, Gerontology Research Center, Baltimore, Maryland 21224 The purpose of the present study was to determine whether age, sex, or angiotensin I-converting enzyme (ACE) genotype influences the effects of strength training (ST) on glucose homeostasis. Nineteen sedentary young (age = 20-30 yr) men ( n = 10) and women ( n = 9) were studied and compared with 21 sedentary older (age = 65-75 yr) men ( n = 12) and women ( n = 9) before and after a 6-mo total body ST program. Fasting insulin concentrations were reduced in young men and in older men with ST ( P