Early healing assessment with optical coherence tomography of everolimus-eluting stents with bioabsorbable polymer (synergy™) at 3 and 6 months after implantation

Objectives In this study we sought to evaluate coverage and apposition of Synergy™ stent at 3 and 6 months after implantation. Background The Pt‐Cr everolimus‐eluting stent with abluminal bioabsorbable polymer (Synergy™) is a new generation drug‐eluting stent with features potentially favoring an ea...

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Veröffentlicht in:Catheterization and cardiovascular interventions 2016-09, Vol.88 (3), p.E67-E73
Hauptverfasser: de la Torre Hernández, Jose M., Tejedor, Paula, Camarero, Tamara Garcia, Duran, Juan M., Lee, Dae-Hyun, Monedero, Jairo, Laso, Fermin Sainz, Calderón, Marcos Alvarez, Veiga, Gabriela, Zueco, Javier
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Sprache:eng
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Zusammenfassung:Objectives In this study we sought to evaluate coverage and apposition of Synergy™ stent at 3 and 6 months after implantation. Background The Pt‐Cr everolimus‐eluting stent with abluminal bioabsorbable polymer (Synergy™) is a new generation drug‐eluting stent with features potentially favoring an early healing process which could make safe a shorter period of dual antiplatelet‐therapy treatment. Methods Prospective, two‐centers study enrolling patients with similar lesions treated with Synergy™ stents undergoing examination with OCT at 3 and 6 months in the respective centers. Blinded analysis was done at a core lab. Co‐primary endpoints were proportion of struts with coverage and with apposition at 3 and 6 months. Results Finally, 22 patients (30 stents) in the 3 months group and 20 patients (30 stents) in the 6 months group were included. There were no significant differences between groups regarding clinical, angiographic measurements, and procedural data. The rate of strut coverage was 94.5% at 3 months and 96.6% at 6 months (P 
ISSN:1522-1946
1522-726X
DOI:10.1002/ccd.26299