Early healing assessment with optical coherence tomography of everolimus-eluting stents with bioabsorbable polymer (synergy™) at 3 and 6 months after implantation
Objectives In this study we sought to evaluate coverage and apposition of Synergy™ stent at 3 and 6 months after implantation. Background The Pt‐Cr everolimus‐eluting stent with abluminal bioabsorbable polymer (Synergy™) is a new generation drug‐eluting stent with features potentially favoring an ea...
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Veröffentlicht in: | Catheterization and cardiovascular interventions 2016-09, Vol.88 (3), p.E67-E73 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Objectives
In this study we sought to evaluate coverage and apposition of Synergy™ stent at 3 and 6 months after implantation.
Background
The Pt‐Cr everolimus‐eluting stent with abluminal bioabsorbable polymer (Synergy™) is a new generation drug‐eluting stent with features potentially favoring an early healing process which could make safe a shorter period of dual antiplatelet‐therapy treatment.
Methods
Prospective, two‐centers study enrolling patients with similar lesions treated with Synergy™ stents undergoing examination with OCT at 3 and 6 months in the respective centers. Blinded analysis was done at a core lab. Co‐primary endpoints were proportion of struts with coverage and with apposition at 3 and 6 months.
Results
Finally, 22 patients (30 stents) in the 3 months group and 20 patients (30 stents) in the 6 months group were included. There were no significant differences between groups regarding clinical, angiographic measurements, and procedural data. The rate of strut coverage was 94.5% at 3 months and 96.6% at 6 months (P |
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ISSN: | 1522-1946 1522-726X |
DOI: | 10.1002/ccd.26299 |