Seroconversion to HIV-1 following a needlestick injury despite combination post-exposure prophylaxis

Post-exposure prophylaxis with antiretroviral drugs for at-risk needlestick injuries has become routine practice and is usually empirical. With increasing numbers of treatment-experienced patients, the choice of antiretroviral may need to be individually tailored. Infection can still occur despite a...

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Veröffentlicht in:	The Journal of infection 2001-07, Vol.43 (1), p.12-15
Hauptverfasser:	HAWKINS, D. A, ASBOE, D, BARLOW, K, EVANS, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents - therapeutic use Biological and medical sciences Hand Injuries - complications HIV Infections - prevention & control HIV Seropositivity - diagnosis HIV Seropositivity - drug therapy HIV Seropositivity - transmission HIV-1 - immunology Human immunodeficiency virus Human immunodeficiency virus 1 Human viral diseases Humans Infectious Disease Transmission, Patient-to-Professional Infectious diseases Male Medical sciences Middle Aged needles Needlestick Injuries - complications Nurses, Male Occupational Exposure - adverse effects prophylaxis seroconversion Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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Beschreibung
Zusammenfassung:	Post-exposure prophylaxis with antiretroviral drugs for at-risk needlestick injuries has become routine practice and is usually empirical. With increasing numbers of treatment-experienced patients, the choice of antiretroviral may need to be individually tailored. Infection can still occur despite attempts to optimize the drug combination used.
ISSN:	0163-4453 1532-2742
DOI:	10.1016/S0163-4453(01)90811-4