L-Threoninol as a Chiral Linker of Azobenzene for the Effective Photo-regulation of DNA Triplex Formation

L-Threoninol as a Chiral Linker of Azobenzene for the Effective Photo-regulation of DNA Triplex Formation

An azobenzene was enantioselectively attached to the 5′-end of oligo(T) through D- or L-threoninol. Photo-isomerization of azobenzene, tethered on L-threoninol, induced much larger change of melting temperature of triplex formation than did that on the D-form.

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Veröffentlicht in:Chemistry letters 2001-07, Vol.30 (7), p.732-733
Hauptverfasser: Takarada, Tohru, Tamaru, Daisuke, Liang, Xingguo, Asanuma, Hiroyuki, Komiyama, Makoto
Format: Artikel
Sprache:eng
Schlagworte:
azobenzene
D-threoninol
L-threoninol
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Beschreibung
Zusammenfassung:An azobenzene was enantioselectively attached to the 5′-end of oligo(T) through D- or L-threoninol. Photo-isomerization of azobenzene, tethered on L-threoninol, induced much larger change of melting temperature of triplex formation than did that on the D-form.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2001.732